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MIGRAINE - INDICATIONS

DEPAKOTE ER is indicated for prophylaxis of migraine headaches in adults. There is no evidence that DEPAKOTE ER is useful in the acute treatment of migraine headaches. Because valproic acid may be a hazard to the fetus, DEPAKOTE ER should be considered for women of childbearing potential only after this risk has been thoroughly discussed with the patient and weighed against the potential benefits of treatment.

The Established Family of DEPAKOTE Formulations: Coverage of DEPAKOTE ER Extends Beyond Migraine 1,3,6,7


Indications/ DEPAKOTE Formulation

DEPAKOTE ER®
(Divalproex Sodium
Extended-Release Tablets)

DEPAKOTE®(Divalproex Sodium
Delayed-Release Tablets)

DEPACON®(Valproate Sodium Injection)

(When Oral Administration Not Feasible)

DEPAKOTE® Sprinkle Capsules

(Divalproex Sodium Coated Particles in Capsules)

Monotherapy for complex partial seizures (in isolation or in association with other seizure types)
(adults or children >10 years)

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Adjunctive therapy for complex partial seizures (in isolation or in association with other seizure types)
(adults or children >10 years)

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Monotherapy for simple and complex absence seizures (adults or children >10 years)

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Adjunctive therapy for simple and complex absence seizures (adults or children >10 years)

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Adjunctive therapy for patients with multiple seizure types that include absence seizures (adults or children >10 years)

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Prophylaxis of migraine headaches
(adults only)

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Treatment of manic episodes associated with bipolar disorder
(adults only)

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Treatment of acute manic or mixed episodes associated with bipolar disorder
(adults only)
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DEPAKOTE® ER Full Prescribing Information DEPAKOTE® Full Prescribing Information
DEPACON® Full Prescribing Information DEPAKOTE® Sprinkle Capsules Full Prescribing Information